**Context:** This work is motivated by a study in Type II diabetes patients and their progression to diabetic retinopathy. Specifically, physicians are interested in identifying risk factors, longitudinal and baseline, for progression. An important …
Our work is motivated by examples from two large cohort studies, the Generation R Study and the Rotterdam Study, in which the analysis models of interest involved non-linear effects, interaction terms or had a longitudinal outcome. As is the case for …